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Article

Complete cure of persistent virus infections by antiviral siRNAs.

Molecular therapy : the journal of the American Society of Gene Therapy - 1 Jan 2006

Saulnier Aure, Pelletier Isabelle, Labadie Karine, Colbère-Garapin Florence

Abstract excerpt

Small interfering RNAs (siRNAs) have been developed as antiviral agents for mammalian cells. The capacity of specific siRNAs to prevent virus infections has been demonstrated, and there is evidence that these new antiviral agents could have a partial therapeutic effect a few days after infection. We investigated the possibility of curing a persistent infection, several months after becoming established, using an...

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Identifiers

PMID: 16157509
DOI: 10.1016/j.ymthe.2005.07.697

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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