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Article

Comparison between E1A gene from oncogenic and non-oncogenic adenoviruses in cellular transformation (Ad E1A conserved region).

Archives of virology - 1 Jan 1993

Leclére V, Huvent I, Verwaerde P, Cousin C, D'Halluin J C

Abstract excerpt

All adenoviruses transform primary BRK cells in vitro, but only cells transformed by oncogenic adenoviruses are tumorigenic for immunocompetent animals. The transforming E1 regions of human Ad 2 and Ad 12 also differ from each other in the frequency in which they can transform BRK cells. We have investigated these properties which can be assigned to the specific domain of the E1A region. For this purpose,...

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Identifiers

PMID: 8379854
DOI: 10.1007/BF01309544

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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