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Article

Analysis of large X-ray-induced mutant populations by denaturing gradient gel electrophoresis.

Radiation research - 1 Aug 1993

Okinaka R T, Anzick S L, Oller A, Thilly W G

Abstract excerpt

To increase the precision by which predominant point mutations can be observed, hypoxanthine guanine phosphoribosyl transferase (HPRT)-deficient mutants selected en masse from large X-irradiated cultures of human lymphoblastoid cells (line TK6) were analyzed by denaturing gradient gel electrophoresis (DGGE). Four independent experiments yielded approximately 7 x 10(3) and 3.2 x 10(3) initial surviving...

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PMID: 8367592

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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