Article
Mapping by admixture linkage disequilibrium in human populations: limits and guidelines.
American journal of human genetics - 1 Oct 1994
Stephens J C, Briscoe D, O'Brien S J
Abstract excerpt
Certain human hereditary conditions, notably those with low penetrance and those which require an environmental event such as infectious disease exposure, are difficult to localize in pedigree analysis, because of uncertainty in the phenotype of an affected patient's relatives. An approach to locating these genes in human cohort studies would be to use association analysis, which depends on linkage disequilibrium...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.