Mapping by admixture linkage disequilibrium in human populations: limits and guidelines.

Article

Mapping by admixture linkage disequilibrium in human populations: limits and guidelines.

American journal of human genetics - 1 Oct 1994

Stephens J C, Briscoe D, O'Brien S J

Abstract excerpt

Certain human hereditary conditions, notably those with low penetrance and those which require an environmental event such as infectious disease exposure, are difficult to localize in pedigree analysis, because of uncertainty in the phenotype of an affected patient's relatives. An approach to loc...

Topics

Alleles
Animals
Cohort Studies
DNA
False Positive Reactions
Feasibility Studies
Gene Frequency
Genetic Diseases, Inborn
Genetic Markers
Genetic Techniques
Guidelines as Topic
Hominidae
Humans
Linkage Disequilibrium
Models, Genetic
Polymorphism, Genetic

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