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Article

Mutations in beta-actin: influence on polymer formation and on interactions with myosin and profilin.

FEBS letters - 23 Aug 1993

Aspenström P, Schutt C E, Lindberg U, Karlsson R

Abstract excerpt

Two beta-actin mutants, one with proline 38 replaced with alanine (P38A) and the other with cysteine-374 replaced with serine (C374S), as well as the wild-type beta-actin, were expressed in the yeast, S. cerevisiae, purified to homogeneity, and analyzed in vitro for polymerizability and interacti...

Topics

Actins
Animals
Contractile Proteins
Deoxyribonuclease I
Egtazic Acid
Humans
Magnesium Chloride
Microfilament Proteins
Mutation
Myosins
Polymers
Potassium Chloride
Profilins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Rabbits

Recombinant Proteins

Saccharomyces cerevisiae

Structure-Activity Relationship

Viscosity

Source

Identifiers

PMID: 8354391
DOI: 10.1016/0014-5793(93)80215-g

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-8354391-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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