Article
Actin structure and function: roles in mitochondrial organization and morphogenesis in budding yeast and identification of the phalloidin-binding site.
Molecular biology of the cell - 1 Dec 1993
Drubin D G, Jones H D, Wertman K F
Abstract excerpt
To further elucidate the functions of actin in budding yeast and to relate actin structure to specific roles and interactions in vivo, we determined the phenotypes caused by 13 charged-to-alanine mutations isolated previously in the single Saccharomyces cerevisiae actin gene. Defects in actin org...
Topics
- Actin Cytoskeleton
- Actins
- Amino Acid Sequence
- Binding Sites
- Cell Nucleus
- Fungal Proteins
- Mitochondria
- Models, Molecular
- Molecular Sequence Data
- Mutagenesis, Site-Directed
- Phalloidine
- Phenotype
- Protein Conformation
- Saccharomyces cerevisiae
- Structure-Activity Relationship