Article
Genetic susceptibility to non-insulin dependent diabetes mellitus and glucose intolerance are located in HLA region.
BMJ (Clinical research ed.) - 17 Jul 1993
Tuomilehto-Wolf E, Tuomilehto J, Hitman G A, Nissinen A, Stengård J, Pekkanen J, Kivinen P, Kaarsalo E, Karvonen M J
Abstract excerpt
OBJECTIVES: To test the hypothesis that the genetic susceptibility to non-insulin dependent diabetes mellitus is the same as that to insulin dependent disease and to see whether glucose intolerance is associated with specific HLA haplotypes. DESIGN: Population based study of men in 1989 first tested for glucose tolerance in 1984. HLA haplotypes, including HLA-A, C, B, DR, and DQ, were defined serologically. HLA...
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