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Article

HLA Class II Allele Analyses Implicate Common Genetic Components in Type 1 and Non-Insulin-Treated Type 2 Diabetes.

The Journal of clinical endocrinology and metabolism - 1 Mar 2020

Jacobi Thomas, Massier Lucas, Klöting Nora, Horn Katrin, Schuch Alexander, Ahnert Peter, Engel Christoph, Löffler Markus, Burkhardt Ralph, Thiery Joachim, Tönjes Anke, Stumvoll Michael, Blüher Matthias, Doxiadis Ilias, Scholz Markus, Kovacs Peter

Abstract excerpt

CONTEXT: Common genetic susceptibility may underlie the frequently observed co-occurrence of type 1 and type 2 diabetes in families. Given the role of HLA class II genes in the pathophysiology of type 1 diabetes, the aim of the present study was to test the association of high density imputed human leukocyte antigen (HLA) genotypes with type 2 diabetes. OBJECTIVES AND DESIGN: Three cohorts (Ntotal = 10 413) from...

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PMID: 31974565
DOI: 10.1210/clinem/dgaa027

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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