Article
Effect of polymorphism in the insulin gene region on IDDM susceptibility and insulin secretion. The Childhood Diabetes in Finland (DiMe) Study Group.
European journal of clinical investigation - 1 Oct 1996
Halminen M, Veijola R, Reijonen H, Ilonen J, Akerblom H K, Knip M
Abstract excerpt
In addition to the major genetic determinants of insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) on chromosome 6, there are also minor genetic risk markers, e.g. in the insulin gene region on chromosome 11p15.5 (IDDM2). We studied the significance of the-23 HphI polymorphism in the insulin gene region (-23 HphI INS) in the Finnish population in combination with HLA...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.