Article
Effect of polymorphism in the insulin gene region on IDDM susceptibility and insulin secretion. The Childhood Diabetes in Finland (DiMe) Study Group.
European journal of clinical investigation - 1 Oct 1996
Halminen M, Veijola R, Reijonen H, Ilonen J, Akerblom H K, Knip M
Abstract excerpt
In addition to the major genetic determinants of insulin-dependent diabetes mellitus (IDDM) in the major histocompatibility complex (MHC) on chromosome 6, there are also minor genetic risk markers, e.g. in the insulin gene region on chromosome 11p15.5 (IDDM2). We studied the significance of the-2...
Topics
- Adolescent
- Alleles
- Diabetes Mellitus, Type 1
- Disease Susceptibility
- Female
- Genotype
- HLA-DQ Antigens
- HLA-DQ beta-Chains
- Humans
- Insulin
- Insulin Secretion
- Male
- Polymorphism, Genetic