Article
Insulin-dependent diabetes and human leucocyte antigens.
Diabetes & metabolism - 1 Mar 1997
Boitard C, Caillat-Zucman S, Timsit J
Abstract excerpt
The association of diabetes with HLA class I alleles in the early 1970s and with HLA class II alleles in the late 1970s provided a crucial, though indirect, indication of the role of immune phenomena in the development of insulin-dependent diabetes mellitus (IDDM). Genotyping of HLA alleles in the mid-1980s opened up a new era. The very precise definition of susceptibility and protection alleles proved to be an...
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