Article
Increased and decreased relative risk for non-insulin-dependent diabetes mellitus conferred by HLA class II and by CD4 alleles.
Clinical genetics - 1 May 1995
Ghabanbasani M Z, Spaepen M, Buyse I, Legius E, Decorte R, Bex M, Marynen P, Bouillon R, Cassiman J J
Abstract excerpt
Non-insulin-dependent diabetes mellitus has been recognized to be heterogeneous in etiology, with multiple subgroups. Several genes or chromosomal regions have been implicated in the development of the disease. In this study the association of HLA class II alleles and genotypes and the associatio...
Topics
- Adult
- Aged
- Alleles
- Base Sequence
- CD3 Complex
- CD4 Antigens
- DNA Primers
- Diabetes Mellitus, Type 2
- Female
- Genetic Predisposition to Disease
- Genotype
- HLA-DQ Antigens
- Humans
- Male
- Middle Aged
- Molecular Sequence Data
- Risk Factors
