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HLA class II alleles and haplotypes in Lithuanian children with type 1 diabetes and healthy children (HLA and type 1 diabetes).

Medicina (Kaunas, Lithuania) - 1 Jan 2010

Skrodenienė Erika, Marčiulionytė Dalia, Padaiga Zilvinas, Jašinskienė Edita, Sadauskaitė-Kuehne Vaiva, Sanjeevi Carani B, Ludvigsson Johnny

Abstract excerpt

OBJECTIVE: Type 1 diabetes mellitus is a slowly progressive autoimmune disease. The genetic background of type 1 diabetes mellitus is polygenic with the major disease locus located in the human leukocytes antigen (HLA) region. High risk and protective alleles, haplotypes, and genotypes have been determined in Lithuanian children with type 1 diabetes mellitus and healthy children. MATERIAL AND METHODS: In this...

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Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

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Share to Infant, Newborn

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PMID: 20966625

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