Article
An association analysis of the HLA gene region in latent autoimmune diabetes in adults.
Diabetologia - 1 Jan 2007
Desai M, Zeggini E, Horton V A, Owen K R, Hattersley A T, Levy J C, Walker M, Gillespie K M, Bingley P J, Hitman G A, Holman R R, McCarthy M I, Clark A
Abstract excerpt
AIMS/HYPOTHESIS: Pathophysiological similarities between latent autoimmune diabetes in adults (LADA) and type 1 diabetes indicate an overlap in genetic susceptibility. HLA-DRB1 and HLA-DQB1 are major susceptibility genes for type 1 diabetes but studies of these genes in LADA have been limited. Our aim was to define patterns of HLA-encoded susceptibility/protection in a large, well characterised LADA cohort, and...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
