Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Constitutive modulation of Raf-1 protein kinase is associated with differential gene expression of several known and unknown genes.

Molecular medicine (Cambridge, Mass.) - 1 Oct 1997

Patel S, Wang F H, Whiteside T L, Kasid U

Abstract excerpt

BACKGROUND: Raf-1, a cytoplasmic serine/threonine protein kinase, plays an important role in mitogen- and damage-responsive cellular signal transduction pathways. Consistent with this notion is the fact that constitutive modulation of expression and/or activity of Raf-1 protein kinase modifies ce...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Base Sequence
Share to Cell Line
Share to DNA, Complementary

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Share to Molecular Sequence Data

Share to Phenotype

Share to RNA, Messenger

Share to Sequence Analysis, DNA

Share to Transfection

Source

Open in PubMed Open full text

Identifiers

PMID: 9392004
PMCID: PMC2230229

Genes

HGS

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-9392004-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Constitutive modulation of Raf-1 protein kinase is associated with differential gene expression of several known and unknown genes.PMID 9392004Read ↗

Transactivation of c-fos and beta-actin genes by raf as a step in early response to transmembrane signals.Semantic proximity Read ↗

Second nature: Biological functions of the Raf‐1 “kinase”Semantic proximity Read ↗

Analysis of the transcriptional program induced by Raf in epithelial cells.Semantic proximity Read ↗

A-Raf: A new star of the family of raf kinases.Semantic proximity Read ↗

Induction of putative tumor-suppressing genes in Rat-1 fibroblasts by oncogenic Raf-1 as evidenced by robot-assisted complex hybridization.Semantic proximity Read ↗

Transformation by Raf and other oncogenes renders cells differentially sensitive to growth inhibition by a dominant negative c-jun mutant.Semantic proximity Read ↗

Role of raf isoforms in signal transduction pathways relevant to leukemia cell proliferation.Semantic proximity Read ↗

An inhibitory Raf-1 mutant suppresses expression of a subset of v-raf-activated genes.Semantic proximity Read ↗

Guilty as charged: B-RAF is a human oncogene.Semantic proximity Read ↗

Three new types of Apaf-1 in mammalian cells.Semantic proximity Read ↗

Serum-, TPA-, and Ras-induced expression from Ap-1/Ets-driven promoters requires Raf-1 kinase.Semantic proximity Read ↗

Loss of Transgelin in Breast and Colon Tumors and in RIE-1 Cells by Ras Deregulation of Gene Expression through Raf-independent PathwaysSemantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.