Article
v-Fps-responsiveness in the Egr-1 promoter is mediated by serum response elements.
Nucleic acids research - 11 May 1992
Alexandropoulos K, Qureshi S A, Rim M, Sukhatme V P, Foster D A
Abstract excerpt
Egr-1, a mitogen-responsive transcription factor, is rapidly induced by v-Fps in the absence of protein synthesis. Thus, Egr-1 is a primary response to the protein-tyrosine kinase activity of v-Fps. To determine the v-Fps-responsive elements in the Egr-1 promoter, deletion mutants of the Egr-1 promoter were used in transient expression assays. A v-Fps expression vector was contransfected into NIH 3T3 cells with...
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