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Article

Expression of H19 does not influence the timing of replication of the Igf2/H19 imprinted region.

Developmental genetics - 1 Jan 1997

Windham C Q, Jones P A

Abstract excerpt

Allele specific timing of replication is believed to be a hallmark of imprinted genes, however recent evidence suggests that this might not be the case for the insulin-like growth factor 2 (Igf2) and H19 locus. In this report, we assayed the timing of replication of Igf2 and H19 in two mouse embryonic cell lines expressing both H19 and Igf2, and one cell line maternally disomic for the Igf2/H19 mouse locus which...

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Identifiers

PMID: 9094209
DOI: 10.1002/(SICI)1520-6408(1997)20:1<29::AID-DVG4>3.0.CO;2-B

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

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Research trail→

Click a neighbor to travelStep 1 · 12 closest

Expression of H19 does not influence the timing of replication of the Igf2/H19 imprinted region.PMID 9094209Read ↗

Allele-specific replication timing of imprinted gene regions.Semantic proximity Read ↗

CTCF regulates asynchronous replication of the imprinted H19/Igf2 domain.Semantic proximity Read ↗

Asynchronous replication timing of imprinted loci is independent of DNA methylation, but consistent with differential subnuclear localization.Semantic proximity Read ↗

Igf2-H19, an imprinted tandem gene, is an important regulator of embryonic development, a guardian of proliferation of adult pluripotent stem cells, a regulator of longevity, and a ‘passkey’ to cancerogenesisSemantic proximity Read ↗

Biallelic transcription of Igf2 and H19 in individual cells suggests a post-transcriptional contribution to genomic imprinting.Semantic proximity Read ↗

Deletion of a silencer element in Igf2 results in loss of imprinting independent of H19Semantic proximity Read ↗

H19 and Igf2 monoallelic expression is regulated in two distinct ways by a shared cis acting regulatory region upstream of H19.Semantic proximity Read ↗

Epigenetic mechanisms underlying the imprinting of the mouse H19 gene.Semantic proximity Read ↗

Paternal imprints can be established on the maternal Igf2-H19 locus without altering replication timing of DNA.Semantic proximity Read ↗

The H19 Transcript Is Associated with Polysomes and May Regulate IGF2 Expression in transSemantic proximity Read ↗

H19 is imprinted in the choroid plexus and leptomeninges of the mouse foetus.Semantic proximity Read ↗

Deletion of a silencer element disruptsH19imprinting independently of a DNA methylation epigenetic switchSemantic proximity Read ↗

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