Article
Allele-specific replication timing in imprinted domains: absence of asynchrony at several loci.
Human molecular genetics - 1 Dec 1995
Kawame H, Gartler S M, Hansen R S
Abstract excerpt
Using a bromodeoxyuridine incorporation method to detect replicated DNA, we studied allele-specific replication of several sites within the human Prader-Willi/Angelman and IGF2/H19 imprinted regions. No obvious allele-specific differences in time of replication were detected at most loci previous...
Topics
- Alleles
- Autoantigens
- Base Sequence
- Bromodeoxyuridine
- Cell Line, Transformed
- DNA
- DNA Replication
- Genomic Imprinting
- HeLa Cells
- Humans
- In Situ Hybridization, Fluorescence
- Insulin-Like Growth Factor II
- Molecular Sequence Data
- Muscle Proteins
- Prader-Willi Syndrome
- RNA, Long Noncoding
- RNA, Untranslated
- Ribonucleoproteins, Small Nuclear
