Article
Differential transcriptional activation by v-myb and c-myb in animal cells and Saccharomyces cerevisiae.
Molecular and cellular biology - 1 Jul 1993
Chen R H, Lipsick J S
Abstract excerpt
The v-myb oncogene and its cellular homolog c-myb encode sequence-specific DNA-binding proteins which regulate transcription from promoters containing Myb-binding sites in animal cells. We have developed a Saccharomyces cerevisiae system to assay transcriptional activation by v-Myb and c-Myb. In yeast strains containing integrated reporter genes, activation was strictly dependent upon both the Myb DNA-binding...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
