Article
Myb-induced transformation.
Critical reviews in oncogenesis - 1 Jan 1996
Wolff L
Abstract excerpt
The c-myb protooncogene has been implicated in the development of avian and murine hematopoietic neoplasms of the myeloid and lymphoid lineages. The transcription factor encoded by this gene has a dual function in oncogenesis because it regulates genes that prevent apoptosis and genes involved in...
Topics
- Animals
- Apoptosis
- Avian Myeloblastosis Virus
- Cell Differentiation
- Cell Division
- Cell Transformation, Neoplastic
- Gene Expression Regulation, Neoplastic
- Humans
- Leukemia
- Mutation
- Oncogene Proteins v-myb
- Proto-Oncogene Proteins
- Proto-Oncogene Proteins c-myb
- Retroviridae Proteins, Oncogenic
- Trans-Activators
- Transcription, Genetic