Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Combinatorial diversity in DR2 haplotypes.

Tissue antigens - 1 Mar 1993

Wade J A, Hurley C K, Hastings A, Ehrenberg P, Johnson A H, Martell R W, du Toit E D

Abstract excerpt

Sequence analysis has identified multiple alleles at two loci that encode for the DR2 specificity. The loci, DRB1 and DRB5, are in linkage disequilibrium which can extend to alleles of the DQ loci. Serologic, cellular, and sequence-specific oligonucleotide probe (SSOP) typing techniques have been used to identify the DR2 haplotypes. In this report, we have characterized by SSOP typing and cDNA/DNA sequence...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Alleles
Share to Base Sequence
Share to DNA

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Haplotypes

Share to Histocompatibility Antigens Class II

Share to HLA-DR Antigens

Share to Molecular Sequence Data

Share to Polymerase Chain Reaction

Source

Identifiers

PMID: 8316942
DOI: 10.1111/j.1399-0039.1993.tb01990.x

Genes

LUM

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Combinatorial diversity in DR2 haplotypes.PMID 8316942Read ↗

A novel DRB1 allele in DR2-positive American blacks.Semantic proximity Read ↗

Sequence analysis of HLA-DR4B1 subtypes: additional first domain variability is detected by oligonucleotide hybridization and nucleotide sequencing.Semantic proximity Read ↗

Direct sequencing of SSP-PCR-amplified cDNA to identify new alleles in the DR52-associated DRB1 group: identification of DRB1*1115, DRB1*1117 and DRB1*1319.Semantic proximity Read ↗

DRw11 haplotypes: continuum of DRB1 diversity augmented by unique DQ/DRw52 associations.Semantic proximity Read ↗

Detection of novel sequence heterogeneity and haplotypic diversity of HLA class II genes.Semantic proximity Read ↗

HLA-DR typing using DNA amplification by the polymerase chain reaction and sequential hybridization to sequence-specific oligonucleotide probes.Semantic proximity Read ↗

Analysis of HLA class II polymorphism using polymerase chain reaction.Semantic proximity Read ↗

Irregular polymerase chain reaction-sequence-specific oligonucleotide hybridization patterns reveal seven new HLA-DRB1 alleles related to DR2, DR3, DR6, DR8, and DR11. Implications for sequence-specific priming.Semantic proximity Read ↗

DNA typing for class II HLA antigens with allele-specific or group-specific amplification. IV. Typing for alleles of the HLA-DR2 group.Semantic proximity Read ↗

Apparent HLA DR triplet due to the coexpression of a DRB5-encoded molecule on a DR1 haplotype.Semantic proximity Read ↗

A comparative study of HLA-DRB1 typing by standard serology and hybridization of non-radioactive sequence-specific oligonucleotide probes to PCR-amplified DNA.Semantic proximity Read ↗

Serologic and molecular studies of two kindreds expressing recombinant HLA DR1/DR2 haplotypes.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.