Article
Detection of novel sequence heterogeneity and haplotypic diversity of HLA class II genes.
Immunogenetics - 1 Jan 1991
Santamaria P, Boyce-Jacino M T, Lindstrom A L, Barbosa J J, Faras A J, Rich S S
Abstract excerpt
Nucleic acid sequences of the second exons of HLA-DRB1, -DRB3/4/5, -DQB1, and -DQA1 genes were determined from 43 homozygous cell lines, representing each of the known class II haplotypes, and from 30 unrelated Caucasian subjects, comprising 60 haplotypes. This systematic sequence analysis was un...
Topics
- Alleles
- Base Sequence
- Biological Evolution
- Genes, MHC Class II
- HLA-DQ Antigens
- HLA-DR Antigens
- Haplotypes
- Humans
- Molecular Sequence Data
- Mutation