Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

DRw11 haplotypes: continuum of DRB1 diversity augmented by unique DQ/DRw52 associations.

Human immunology - 1 Oct 1991

Lee K W, Johnson A H, Tang T, Yu W Y, Karr R W, Hurley C K

Abstract excerpt

cDNA sequencing of the first domains of DRB1, DRB3, DQA1, and DQB1 alleles was used to examine the extent of diversity in American black individuals expressing several DRw11 haplotypes. In addition to previously described DRw11 alleles, DRB1*1102 and DRB1*1103, two new DRB1 alleles, DRB1*11012 and DRB1*11042, were identified which differ from previously described alleles at the nucleic acid but not at the protein...

Topics

Amino Acid Sequence
Base Sequence
Biological Evolution
Black People
Genetic Variation
HLA-DQ Antigens
HLA-DR Antigens
HLA-DR Serological Subtypes
HLA-DRB1 Chains
Haplotypes
Histocompatibility Antigens Class II

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Humans

Molecular Sequence Data

Serotyping

United States

Black or African American

Source

Identifiers

PMID: 1744003
DOI: 10.1016/0198-8859(91)90112-m

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1744003-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

DRw11 haplotypes: continuum of DRB1 diversity augmented by unique DQ/DRw52 associations.PMID 1744003Read ↗

New DQw1 diversity identified within DRw12 and DRw14 haplotypes.Semantic proximity Read ↗

Two divergent routes of evolution gave rise to the DRw13 haplotypes.Semantic proximity Read ↗

A new DRB1 allele (DRB1*1125) sharing DR11 and DR8 sequence motifs.Semantic proximity Read ↗

New DRB1*1120 allele; another example of the transition between the DR11 and DR13 families of alleles.Semantic proximity Read ↗

Relative frequencies of DRB1*11 alleles and their DRB3 associations in five major population groups in a United States bone marrow registry.Semantic proximity Read ↗

Detection of four novel alleles: DRB1*1130, DRB1*13072, DRB1*1315 and DRB1*1331.Semantic proximity Read ↗

Identification of four new DR52-associated DRB1 alleles: DRB1*1424, *1425, *1323 and *1324.Semantic proximity Read ↗

DRw8 microvariation: a new DRB1 allele identified in association with DQw7 in American blacks.Semantic proximity Read ↗

A new DR14 allele (DRB1*1411) containing a short DR11 sequence and its haplotypic association.Semantic proximity Read ↗

Two new HLA DRB1 alleles found in African Americans: implications for balancing selection at positions 57 and 86.Semantic proximity Read ↗

A description of a new DR allele, DRB1*1113.Semantic proximity Read ↗

Strategy for definition of DR/DQ haplotypes in the 4AOHW cell panel using noncoding sequence polymorphisms.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.