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Article

N-ras gene mutations in acute myeloid leukemia: accurate detection by solid-phase minisequencing.

International journal of cancer - 12 Mar 1992

Syvänen A C, Söderlund H, Laaksonen E, Bengtström M, Turunen M, Palotie A

Abstract excerpt

Mutations in the N-ras gene are found in one-third of patients with acute myeloid leukemia. The N-ras mutations could serve as markers for residual cells, if a highly sensitive method for detecting the mutations was available. We applied a new method, solid-phase minisequencing, to analyze bone-marrow cells from 16 patients with acute myeloid leukemia for mutations in codon 12, 13 and 61 of the N-ras gene. In the...

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Identifiers

PMID: 1544704
DOI: 10.1002/ijc.2910500508

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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