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Article

Multivariate genetic analysis of apo AI concentration and HDL subfractions: evidence for major locus pleiotropy.

Genetic epidemiology - 1 Jan 1993

Blangero J, Williams-Blangero S, Mahaney M C

Abstract excerpt

A major locus influencing apolipoprotein AI (apo AI) serum levels was detected using data from the Donner Laboratory Family Study. This locus accounts for 46% of the phenotypic variability in apo AI levels. Multivariate segregation analysis revealed that this major locus also has significant pleiotropic effects on the relative distribution of high density lipoproteins.

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Identifiers

PMID: 8314070
DOI: 10.1002/gepi.1370100648

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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