Article
Two-locus and bivariate segregation analysis of HDL-C and apo AI.
Genetic epidemiology - 1 Jan 1993
Xu J F, Prenger V L, Coresh J, Beaty T H
Abstract excerpt
Two-locus and bivariate segregation analyses of HDL-C and apo AI were carried out using the GAW8 Berkeley data set. For HDL-C, results are ambiguous. Both the mixed environmental model and the mixed Mendelian model fit the data equally well. For apo AI, however, univariate one-locus segregation analysis suggests a Mendelian major gene controlling its levels. Moreover, two-locus analysis suggests a second major...
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