Genotype at a major locus with large effects on apolipoprotein B levels predicts familial combined hyperlipidemia.

doi:10.1002/gepi.1370100406

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Article

Genotype at a major locus with large effects on apolipoprotein B levels predicts familial combined hyperlipidemia.

Genetic epidemiology - 1 Jan 1993

Jarvik G P, Beaty T H, Gallagher P R, Coates P M, Cortner J A

Abstract excerpt

A sample enriched for familial combined hyperlipidemia (FCHL) was examined for evidence of an association between genotype at an apolipoprotein B (apoB) elevating locus defined by complex segregation analysis and FCHL. Complex segregation analysis detected a locus with a large effect on plasma ap...

Topics

Adolescent
Adult
Alleles
Apolipoproteins B
Female
Genes, Regulator
Genotype
Humans
Hyperlipidemia, Familial Combined
Hyperlipoproteinemias
Male

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