Article
Genotype at a major locus with large effects on apolipoprotein B levels predicts familial combined hyperlipidemia.
Genetic epidemiology - 1 Jan 1993
Jarvik G P, Beaty T H, Gallagher P R, Coates P M, Cortner J A
Abstract excerpt
A sample enriched for familial combined hyperlipidemia (FCHL) was examined for evidence of an association between genotype at an apolipoprotein B (apoB) elevating locus defined by complex segregation analysis and FCHL. Complex segregation analysis detected a locus with a large effect on plasma apoB levels and was used to compute the most probable genotype of family members. None of the 35 normolipidemic adults...
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