Article
Genetic analysis of apolipoprotein A-I in two dietary environments.
American journal of human genetics - 1 Sept 1990
Blangero J, MacCluer J W, Kammerer C M, Mott G E, Dyer T D, McGill H C
Abstract excerpt
Although of great clinical and biological importance, the role of genotype-diet interaction in lipoprotein metabolism and atherosclerosis is still poorly understood. We analyzed serum apolipoprotein A-I (apo A-I) concentrations of approximately 600 pedigreed baboons that were fed two dietary regimens: (1) a basal diet and (2) an atherogenic (high-cholesterol, saturated-fat) diet. Complex segregation analysis was...
Topics
- Animals
- Apolipoprotein A-I
- Apolipoproteins A
- Diet
- Diet, Atherogenic
- Female
- Genes, Recessive
- Genotype
- Male
- Models, Genetic
- Papio
- Phenotype