Segregation analysis of two-locus models regulating apolipoprotein-A1 levels.

doi:10.1002/(SICI)1098-2272(1998)15:1<73::AID-GEPI6>3.0.CO;2-5

Back to search

Article

Segregation analysis of two-locus models regulating apolipoprotein-A1 levels.

Genetic epidemiology - 1 Jan 1998

Juo S H, Beaty T H, Xu J, Prenger V L, Coresh J, Kwiterovich P O

Abstract excerpt

For quantitative traits associated with risk to complex diseases, such as heart disease, single major locus models are likely to be too simplistic. Currently, researchers have begun to use oligogenic models of inheritance, but the resolving power of these models remains to be determined. As the m...

Topics

Apolipoprotein A-I
Chromosome Mapping
Coronary Angiography
Coronary Disease
Female
Genetics, Population
Genotype
Humans
Linear Models
Male
Meiosis
Middle Aged
Models, Genetic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.