Article
Segregation analysis of two-locus models regulating apolipoprotein-A1 levels.
Genetic epidemiology - 1 Jan 1998
Juo S H, Beaty T H, Xu J, Prenger V L, Coresh J, Kwiterovich P O
Abstract excerpt
For quantitative traits associated with risk to complex diseases, such as heart disease, single major locus models are likely to be too simplistic. Currently, researchers have begun to use oligogenic models of inheritance, but the resolving power of these models remains to be determined. As the major apoprotein of high density lipoprotein (HDL), apolipoprotein A1 (apo-A1) is generally accepted as a protective...
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