Article
A major locus influencing plasma high-density lipoprotein cholesterol levels in the San Antonio Family Heart Study. Segregation and linkage analyses.
Arteriosclerosis, thrombosis, and vascular biology - 1 Oct 1995
Mahaney M C, Blangero J, Rainwater D L, Comuzzie A G, VandeBerg J L, Stern M P, MacCluer J W, Hixson J E
Abstract excerpt
To detect and measure the effects of a single locus on quantitative variation in plasma concentrations of HDL cholesterol (HDL-C), we conducted statistical genetic analyses on data from 526 Mexican American individuals in 25 randomly ascertained pedigrees. By using maximum-likelihood complex segr...
Topics
- Adolescent
- Adult
- Age Factors
- Aged
- Aged, 80 and over
- Alleles
- Cholesterol, HDL
- Female
- Genetic Linkage
- Humans
- Male
- Mexican Americans
- Middle Aged
- Sex Factors