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Article

Identification by site-directed mutagenesis of amino acids in the B2 subsite of bovine pancreatic ribonuclease A.

Protein engineering - 1 Nov 1993

Tarragona-Fiol A, Eggelte H J, Harbron S, Sanchez E, Taylorson C J, Ward J M, Rabin B R

Abstract excerpt

In addition to hydrolysing RNA, bovine pancreatic ribonuclease splits esters of pyrimidine nucleoside 3'-phosphates, including dinucleotides. For a series of 3':5'-linked dinucleotides of general structure CpN, where N is a 5' linked nucleoside, kcat for the release of N varies enormously with the precise structure of N. Structural studies have been interpreted to indicate that the group N interacts with a...

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Identifiers

PMID: 8309938
DOI: 10.1093/protein/6.8.901

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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