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Article

Ribonuclease A mutant His119 Asn: the role of histidine in catalysis.

FEBS letters - 25 Nov 1996

Panov K I, Kolbanovskaya E Y, Okorokov A L, Panova T B, Terwisscha van Scheltinga A C, Karpeisky MYa, Beintema J J

Abstract excerpt

Bovine pancreatic ribonuclease A (RNase A) has been widely used as a convenient model for structural and functional studies. The enzyme catalyzes cleavage of phosphodiester bonds in RNA and related substrates. Three amino acid residues located at the active site of RNase A (His12, His119, and Lys...

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PMID: 8946953
DOI: 10.1016/s0014-5793(96)01173-8

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 1 Sept 2026. Prepared record publication-8946953-2026-09-01.1. Manifest publication-graph-cohort-2026-09-01.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 1 Sept 2026.

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