Article
Role of aspartic acid 121 in human pancreatic ribonuclease catalysis.
Molecular and cellular biochemistry - 1 Jul 2005
Gaur Deepak, Batra Janendra K
Abstract excerpt
Bovine pancreatic ribonuclease (RNase A) is one of the most well studied enzymes of the ribonuclease family, unlike its human counterpart, the human pancreatic ribonuclease (HPR), whose physiological role in the body is not clearly understood. Human pancreatic ribonuclease consists of 128 amino acids and the main residues located in the active site of RNase A are also conserved in HPR. In the current study, to...
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