Article
Allele loss and point mutation in codons 12 and 61 of the c-Ha-ras oncogene in carcinogen-transformed human breast epithelial cells.
Molecular carcinogenesis - 1 Jan 1994
Zhang P L, Calaf G, Russo J
Abstract excerpt
There is significant evidence that the ras oncogene plays a role in experimental mammary carcinogenesis; the evidence in human breast cancer, however, is more limited. We induced the expression of transformation phenotypes in the human breast epithelial cell line MCF-10F with the chemical carcino...
Topics
- Adult
- Alleles
- Animals
- Base Sequence
- Breast
- Breast Neoplasms
- Carcinogenicity Tests
- Carcinogens
- Cell Line
- Cell Transformation, Neoplastic
- Codon
- DNA Probes
- DNA, Neoplasm