Transforming and oncogenic potential of activated c-Ha-ras in three immortalized human breast epithelial cell lines.

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Article

Transforming and oncogenic potential of activated c-Ha-ras in three immortalized human breast epithelial cell lines.

Anticancer research - 1 Jan 2000

Wang B, Soule H D, Miller F R

Abstract excerpt

The ability of activated c-Ha-ras (codon 12 valine) to transform human breast epithelial cells varied for three different immortalized normal human breast epithelial cell lines established from two different women. Although activated c-Ha-ras may transform and induce a preneoplastic phenotype in...

Topics

Animals
Breast
Breast Neoplasms
Carcinoma, Squamous Cell
Cell Division
Cell Line, Transformed
Cell Transformation, Neoplastic
Epithelial Cells
Female
Genes, ras
Genetic Variation
Humans
Mice
Mice, Nude
Polymerase Chain Reaction
Proto-Oncogene Proteins p21(ras)
Recombinant Proteins
Transfection

Source

Open in PubMed

Identifiers

PMID: 9494538

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-9494538-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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