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Article

Activated c-Ha-ras is not sufficient to produce the preneoplastic phenotype of human breast cell line MCF10AT.

Anticancer research - 1 Jan 2000

Miller F R, Pauley R J, Wang B

Abstract excerpt

MCF10AT cells are human breast epithelial cells which are able to establish preneoplastic lesions in immune deficient mice. Although, the preneoplastic phenotype was observed following transfection with a mutated c-Ha-ras (codon 12 valine), clones of MCF10AT are unable to form lesions in vivo. Restriction size fragment analysis was used to confirm that a clone unable to form the preneoplastic lesions retained the...

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PMID: 8712698

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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