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Chromosome 17p13.2 transfer reverts transformation phenotypes and Fas-mediated apoptosis in breast epithelial cells.

Molecular carcinogenesis - 1 Apr 2004

Lareef Mohamed H, Tahin Quivo, Song Joon, Russo Irma H, Mihaila Dana, Slater Carolyn M, Balsara Binaifer, Testa Joseph R, Broccoli Dominique, Grobelny Jennifer V, Mor Gil, Cuthbert Andrew, Russo Jose

Abstract excerpt

Transformation of the human breast epithelial cells (HBEC) MCF-10F with the carcinogen benz(a)pyrene (BP) into BP1-E cells resulted in the loss of the chromosome 17 p13.2 locus (D17S796 marker) and formation of colonies in agar-methocel (colony efficiency (CE)), loss of ductulogenic capacity in collagen matrix, and resistance to anti-Fas monoclonal antibody (Mab)-induced apoptosis. For testing the role of that...

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PMID: 15057875
DOI: 10.1002/mc.20014

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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