Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin.

The Journal of investigative dermatology - 1 Apr 1990

van der Schroeff J G, Evers L M, Boot A J, Bos J L

Abstract excerpt

Activated ras oncogenes have been detected in a variety of human malignancies. Activation of ras oncogenes usually occurs by point mutations within specific codons of the H-ras, N-ras, and K-ras genes. For the present study, DNA was isolated from 30 basal cell carcinomas (BCC) and 12 squamous cell carcinomas (SCC). After amplification of genomic DNA by using the polymerase chain reaction, the occurrence of point...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aged
Share to Carcinoma, Squamous Cell
Share to DNA, Neoplasm

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Gene Expression Regulation, Neoplastic

Share to Genes, ras

Share to Mutation

Share to Polymerase Chain Reaction

Share to Skin Neoplasms

Source

Identifiers

PMID: 2179417
DOI: 10.1111/1523-1747.ep12874504

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Ras oncogene mutations in basal cell carcinomas and squamous cell carcinomas of human skin.PMID 2179417Read ↗

Ras gene mutation and amplification in human nonmelanoma skin cancers.Semantic proximity Read ↗

Analysis of ras oncogene mutations in human squamous cell carcinoma of the head and neck.Semantic proximity Read ↗

K-ras activation in premalignant and malignant epithelial lesions of the human uterus.Semantic proximity Read ↗

Concurrent Mutations of K-ras Oncogene at Codons 12 and 22 in Colon CancerSemantic proximity Read ↗

Low incidence of point mutation at codon 12 of K-ras proto-oncogene in squamous cell carcinoma of the upper aerodigestive tract.Semantic proximity Read ↗

Codon 12 Harvey-ras mutations are rare events in non-melanoma human skin cancer.Semantic proximity Read ↗

Preferential DNA Damage and Poor Repair Determine ras Gene Mutational Hotspot in Human CancerSemantic proximity Read ↗

Allele loss and point mutation in codons 12 and 61 of the c-Ha-ras oncogene in carcinogen-transformed human breast epithelial cells.Semantic proximity Read ↗

Far less frequent mutations in ras genes than in the p53 gene in skin tumors of xeroderma pigmentosum patients.Semantic proximity Read ↗

Prevalence of RAS oncogene mutation in head and neck carcinomas.Semantic proximity Read ↗

Analysis of ras gene mutations in human hepatic malignant tumors by polymerase chain reaction and direct sequencing.Semantic proximity Read ↗

The ras oncogenes in human lung cancer.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.