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Article

Reduced expression and rare genomic alteration of nm23-H1 in human hepatocellular carcinoma and hepatoma cell lines.

Journal of gastroenterology - 1 Jun 1998

Fujimoto Y, Ohtake T, Nishimori H, Ikuta K, Ohhira M, Ono M, Kohgo Y

Abstract excerpt

We investigated the expression and genomic alteration of nm23-H1 (which encodes a nucleoside diphosphate, kinase A) in 12 human hepatocellular carcinomas (HCCs) and four hepatoma cell lines. The expression of nm23-H1 protein was significantly reduced in HCCs with intrahepatic metastasis (72%) compared with expression in HCCs without intrahepatic metastasis (38%). However, in two of three HCCs examined that had...

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Identifiers

PMID: 9658316
DOI: 10.1007/s005350050098

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HLF

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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