Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma.

doi:10.1016/0140-6736(91)91444-y

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Article

Association of nm23-H1 allelic deletions with distant metastases in colorectal carcinoma.

Lancet (London, England) - 21 Sept 1991

Cohn K H, Wang F S, Desoto-LaPaix F, Solomon W B, Patterson L G, Arnold M R, Weimar J, Feldman J G, Levy A T, Leone A

Abstract excerpt

A prospective study analysed the prognostic value of nm23-H1 allelic deletions in colorectal cancer. Of 21 patients with no evidence of distant metastases at initial operation, 11 showed nm23-H1 allelic deletions (including 1 homozygous deletion); 10 had no nm23-H1 deletions. After median follow-...

Topics

Aged
Alleles
Chromosome Deletion
Colorectal Neoplasms
DNA Probes
Humans
Middle Aged
Neoplasm Metastasis
Predictive Value of Tests
Prognosis
Prospective Studies

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