Increased expression of the nme1 gene is associated with metastasis in epithelial ovarian cancer

doi:10.1002/ijc.2910640308

Article

Increased expression of the nme1 gene is associated with metastasis in epithelial ovarian cancer

22 Jun 1995

Abstract excerpt

The genetic events involved in the development of metastases of epithelial ovarian cancer are largely unknown. One gene postulated to play a role in tumour metastasis suppression is NME1 (nm23-H1), and an inverse relationship between NME1 expression and metastatic potential has been observed for some solid tumours. In this study we have investigated the levels of mRNA expression of the 2 isoforms of the NME gene,...

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