Article
A mutant human histocompatibility leukocyte antigen DR molecule associated with invariant chain peptides.
The Journal of experimental medicine - 1 Feb 1994
Mellins E, Cameron P, Amaya M, Goodman S, Pious D, Smith L, Arp B
Abstract excerpt
From a human histocompatibility leukocyte antigen (HLA)-DR/DQ hemizygous, B lymphoblastoid progenitor, we isolated a cell line, 10.24.6, with a DR alpha missense mutation (96P-->96S), which results in an N-linked carbohydrate addition at position 94 in the DR alpha 2 domain. Several features of 1...
Topics
- Amino Acid Sequence
- Antigen-Presenting Cells
- Antigens, Differentiation, B-Lymphocyte
- Carbohydrates
- Cell Line
- Chromatography, High Pressure Liquid
- Conserved Sequence
- Detergents
- HLA-DR Antigens
- Histocompatibility Antigens Class II
- Humans
- Molecular Sequence Data
- Mutation
- Peptides