Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.

doi:10.1093/genetics/135.3.677

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Article

Isolation and characterization of chromosome-gain and increase-in-ploidy mutants in yeast.

Genetics - 1 Nov 1993

Chan C S, Botstein D

Abstract excerpt

We have developed a colony papillation assay for monitoring the copy number of genetically marked chromosomes II and III in Saccharomyces cerevisiae. The unique feature of this assay is that it allows detection of a gain of the marked chromosomes even if there is a gain of the entire set of chrom...

Topics

Alleles
Chromosome Mapping
Chromosomes, Fungal
Cloning, Molecular
DNA, Fungal
Flow Cytometry
Genes, Fungal
Genes, Recessive
Genetic Complementation Test
Genetic Markers
Mutation
Ploidies
Saccharomyces cerevisiae

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