Article
Functional interaction between the PKC1 pathway and CDC31 network of SPB duplication genes.
Genetics - 1 Aug 2000
Khalfan W, Ivanovska I, Rose M D
Abstract excerpt
The earliest known step in yeast spindle pole body (SPB) duplication requires Cdc31p and Kar1p, two physically interacting SPB components, and Dsk2p and Rad23p, a pair of ubiquitin-like proteins. Components of the PKC1 pathway were found to interact with these SPB duplication genes in two independent genetic screens. Initially, SLG1 and PKC1 were obtained as high-copy suppressors of dsk2Delta rad23Delta and a...
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