Article
Frequent ploidy changes in growing yeast cultures.
Current genetics - 1 Oct 2018
Harari Yaniv, Ram Yoav, Kupiec Martin
Abstract excerpt
Ploidy is considered a very stable cellular characteristic. Although rare, changes in ploidy play important roles in the acquisition of long-term adaptations. Since these duplications allow the subsequent loss of individual chromosomes and accumulation of mutations, changes in ploidy can also cause genomic instability, and have been found to promote cancer. Despite the importance of the subject, measuring the...
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