Article
Genetic interactions between CDC31 and KAR1, two genes required for duplication of the microtubule organizing center in Saccharomyces cerevisiae.
Genetics - 1 Jun 1994
Vallen E A, Ho W, Winey M, Rose M D
Abstract excerpt
KAR1 encodes an essential component of the yeast spindle pole body (SPB) that is required for karyogamy and SPB duplication. A temperature-sensitive mutation, kar1-delta 17, mapped to a region required for SPB duplication and for localization to the SPB. To identify interacting SPB proteins, we isolated 13 dominant mutations and 3 high copy number plasmids that suppressed the temperature sensitivity of kar1-delta...
Read the complete abstract on PubMedTopics
Share this publication in a Topic to start or enrich a Post.
