Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.

Genetics - 1 Feb 2014

Covo Shay, Puccia Christopher M, Argueso Juan Lucas, Gordenin Dmitry A, Resnick Michael A

Abstract excerpt

Gain or loss of chromosomes resulting in aneuploidy can be important factors in cancer and adaptive evolution. Although chromosome gain is a frequent event in eukaryotes, there is limited information on its genetic control. Here we measured the rates of chromosome gain in wild-type yeast and sister chromatid cohesion (SCC) compromised strains. SCC tethers the newly replicated chromatids until anaphase via the...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Aneuploidy
Share to Chromatids
Share to Chromosomal Proteins, Non-Histone

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Chromosomes, Fungal

Share to Cohesins

Share to Diploidy

Share to Drug Resistance, Fungal

Share to Gene Amplification

Source

Open in PubMed Open full text

Identifiers

PMID: 24298060
DOI: 10.1534/genetics.113.159202
PMCID: PMC3914611

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The sister chromatid cohesion pathway suppresses multiple chromosome gain and chromosome amplification.PMID 24298060Read ↗

Stimulation of adaptive gene amplification by origin firing under replication fork constraintSemantic proximity Read ↗

The effect of spontaneous mutations on CUP1 copy number and copper tolerance in Saccharomyces cerevisiae.Semantic proximity Read ↗

Mutability and mutational spectrum of chromosome transmission fidelity genes.Semantic proximity Read ↗

Massive Amplification at an Unselected Locus Accompanies Complex Chromosomal Rearrangements in Yeast.Semantic proximity Read ↗

Mitotic systemic genomic instability in yeastSemantic proximity Read ↗

Functional characterization of the Saccharomyces cerevisiae protein Chl1 reveals the role of sister chromatid cohesion in the maintenance of spindle length during S-phase arrest.Semantic proximity Read ↗

Heterozygous screen in Saccharomyces cerevisiae identifies dosage-sensitive genes that affect chromosome stability.Semantic proximity Read ↗

Arabidopsis COPPER MODIFIED RESISTANCE1/PATRONUS1 is essential for growth adaptation to stress and required for mitotic onset control.Semantic proximity Read ↗

Environmental change drives accelerated adaptation through stimulated copy number variation.Semantic proximity Read ↗

Selective ploidy ablation, a high-throughput plasmid transfer protocol, identifies new genes affecting topoisomerase I-induced DNA damage.Semantic proximity Read ↗

Genome-destabilizing effects associated with top1 loss or accumulation of top1 cleavage complexes in yeast.Semantic proximity Read ↗

Chl1p, a DNA helicase-like protein in budding yeast, functions in sister-chromatid cohesion.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.