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Article

Regulation of canonical Wnt signaling by Brachyury is essential for posterior mesoderm formation.

Developmental cell - 1 Jul 2008

Martin Benjamin L, Kimelman David

Abstract excerpt

The T box transcription factor Brachyury is essential for the formation of the posterior body in all vertebrates, although its critical transcriptional targets have remained elusive. Loss-of-function studies of mouse Brachyury and the zebrafish Brachyury ortholog Ntl indicated that Brachyury plays a more significant role in higher vertebrates than lower vertebrates. We have identified a second zebrafish Brachyury...

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Identifiers

PMID: 18606146
DOI: 10.1016/j.devcel.2008.04.013
PMCID: PMC2601683

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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