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Article

Subtraction cloning of H-rev107, a gene specifically expressed in H-ras resistant fibroblasts.

Oncogene - 1 Feb 1994

Hajnal A, Klemenz R, Schäfer R

Abstract excerpt

We have isolated by subtractive hybridization a novel gene, called H-rev107, which is specifically expressed in a phenotypic revertant of H-ras transformed 208F rat fibroblasts. Apart from oncogene revertants, strong expression of H-rev107 was found in REF52 and EK-3 cells, two fibroblast lines resistant to transformation by activated H-ras oncogenes. In contrast, transformation-sensitive fibroblasts like 208F or...

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PMID: 8290259

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