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Article

Participation of p97Eps8 in Src-mediated transformation.

The Journal of biological chemistry - 12 Mar 2004

Leu Tzeng-Horng, Yeh Hsu Hua, Huang Ching-Chung, Chuang Ya-Chun, Su Shu Li, Maa Ming-Chei

Abstract excerpt

Histone acetylase and histone deacetylase are two crucial enzymes that determine the structure of chromatin, regulating gene expression. In this study, we observed that trichostatin A (TSA), a specific histone deacetylase inhibitor, could effectively inhibit the growth of v-Src-transformed (IV5) cells and abrogate their ability to form colonies in soft agar. Further analysis demonstrated that, although TSA...

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PMID: 14699156
DOI: 10.1074/jbc.M309884200

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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