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Article

Suppression of the transformed phenotype in hybrids of human T-cell leukemia virus type I tax-transformed rat fibroblasts and normal human fibroblasts.

Experimental cell research - 1 Nov 1994

Inoue H, Yamaoka S, Imamura M, Hatanaka M

Abstract excerpt

We have isolated and characterized hybrid cell lines derived from Rat-2 cells transformed by the human T-cell leukemia virus type-I (HTLV-I) Tax protein fused with WI-38 normal human fibroblasts. These hybrid cells (designated as RTW cells) showed contact inhibition after growing to confluency, loss of anchorage-independent growth in 0.33% soft agar, and inability to form tumors in athymic mice. Assays of...

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Identifiers

PMID: 7957683
DOI: 10.1006/excr.1994.1316

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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