Article
Suppression of the transformed phenotype in hybrids of human T-cell leukemia virus type I tax-transformed rat fibroblasts and normal human fibroblasts.
Experimental cell research - 1 Nov 1994
Inoue H, Yamaoka S, Imamura M, Hatanaka M
Abstract excerpt
We have isolated and characterized hybrid cell lines derived from Rat-2 cells transformed by the human T-cell leukemia virus type-I (HTLV-I) Tax protein fused with WI-38 normal human fibroblasts. These hybrid cells (designated as RTW cells) showed contact inhibition after growing to confluency, l...
Topics
- Animals
- Blotting, Western
- Cell Adhesion
- Cell Division
- Cell Fusion
- Cell Line
- Cell Line, Transformed
- Cell Transformation, Viral
- Chloramphenicol O-Acetyltransferase
- Fibroblasts
- Gene Expression
- Gene Products, tax
- Human T-lymphotropic virus 1
- Humans
- Hybrid Cells
- Mice
- Mice, Nude
- Phenotype